I did not know that Iowa allowed skunks as pets! They sure are cute, except for the smell part :D
Rats and mice can be adorable too :) I have never owned either, but when I was a kid, I had hamsters and I used to love them so much!
It largely depends on the state laws, the nature of the goods sold and other factors. I am not sure about Texas, but in California for example, a permit is definitely needed for such activities.
I agree with Eric. Logically, I don't see that permits have any effect on increasing the value of the property. However, the lack thereof might cause the property price to decrease, should you want to sell it at some point.
I don't think I would want to operate an AirBnB either. It's just too much hassle, and the level of profitability is somewhat low from what I hear. I just don't think it's worth the headache.